Monday, February 8, 2010

Top 30 Science Blogs at Times Online - Eureka Zone

The Eureka Zone science blog at the NY Times has a list of their top 30 science blogs.  If you are looking for science reading this is a great place to start.  I only wish there was a Chemistry blog or two on their list.

Times Online - Eureka Zone: Eureka's Top 30 Science Blogs

Friday, February 5, 2010

George Whitesides Discusses Designing a "Lab on a Stamp"




This talk is listed at the Ted.com site as "A Lab the Size of a Postage Stamp," but it should really be "A ON a Postage Stamp."  He talks about the ingenious way his group has designed "devices" for medical diagnostics from paper.  This makes it very inexpensive as well as easily disposable - no sharps or bio-waste to worry about, you can just burn the device when you are done.

George Whitesides is an Organic Chemist from Harvard - I would love to hear him talk about his work on Self-Assembly, but this is pretty cool too.  To quote from his Bio at Ted:
He's co-founded a nonprofit called Diagnostics for All that aims to provide dirt-cheap diagnostic devices, to provide healthcare in a world where cost is everything.
While sharing some of his experience, he also has some interesting observations of the nature of our society, given that the cost of healthcare has been such a topic of discussion lately.

Monday, December 28, 2009

Sugary Antifreeze Molecule Found In Alaskan Beetle



I've been visiting family out of town - we got here just in time to be snowed-in for Christmas. So I thought some wintry chemistry would be appropriate.

Slashdot recently had a listing about a new anti-freeze molecule that has recently been found in the Alaskan beetle, Upis ceramboides. Anti-freeze molecules have been observed in a variety of plants and animals that help them resist damage from the formation of ice crystals in their tissues. All previous anti-freeze molecules have been proteins, but this new one is a sugar. It may also have a lipid component, but that isn't clear.


The sugar, xylomannan, is a polymer of mannose and xylose. Originally the researchers assumed that the anti-freeze compound in their beetles was a protein, like other known anti-freeze compounds. However they couldn't visualize it with electrophoresis, and the UV-vis and NMR spectra didn't show any sign of peptide bonds or aromatic sidechains like tyrosine or phenylalanine. Instead, the NMR was consistent with a sugar molecule, which was confirmed by GC/MS.


Research Article: A nonprotein thermal hysteresis-producing xylomannan antifreeze in the freeze-tolerant Alaskan beetle Upis ceramboides

Slashdot Science Story | New Antifreeze Molecule Isolated In Alaskan Beetle

Friday, December 25, 2009